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Potential Consequences of Untreated B12 Deficiency in Thalassemia Untreated B12 deficiency can lead to serious problems for those with thalassemia

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Due to not finding any study similar to ours, we used the data needed for sample size calculation from Kwok et al

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severe thiamine deficiency, while rare, can cause Wernickes encephalopathy in hyperemesis gravidarum, and inadequate B is associated with anemia and neurologic issues in the newborn