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377 Although they exhibit great potential for clinical transformation in the evaluation of antitumor effects, shortcomings include low fluorescence and dark toxicity, which hinders their further biological application

Mansour A, Abdollahi M, Mirahmad M, Motamed S, Khorasanian AS, Mirlohi SH

Proteomics Insights 8:110

Autophagy is a process of degradation of cellular components by the lysosomal pathway as an adaptive response to stress, to mediate cytoprotective responses and enhance energy production

Furthermore, when cultured in hypoxic conditions (5% O 2 ), BM-MSCs have shown an incremented expression of genes involved in chondrogenic differentiation (ACAN, KRT19, BARX1), immunomodulation (CXCL5, SFN), and cell survival and proliferation (GPX3, TXNIP) compared to BM-MSCs cultured under atmospheric O 2

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