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PMC 5560858

Because homocysteine is highly toxic and enhances the vulnerability of cells to oxidative injury, hyperhomocysteinemia is associated with the development of ALD (26)

When practitioners build protocols, they often begin with the fewest moving parts possible

In contrast, organicinorganic hybrid nanocarriers have extremely high editability and can be easily manipulated to achieve responsive drug release

Recent evidence has highlighted the role of oxidative stress and neuronal dysfunction in the pathogenesis of peripheral neuropathy, providing a rationale for exploring agents with neuroprotective and antioxidant properties 10

Meanwhile, exercise increases the blood flow back to the heart leading to increased left ventricle end-diastolic volume and force of contraction (Frank-Starling mechanism)