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However, discussing a single mechanism may neglect other targets of auxiliary intervention since the function of NAD+ itself is also an important part of the mitochondrial respiratory chain, wherein it interacts with most of the intracellular molecules

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Moreover, a variant in CPT2 (rs1799821) was confirmed to be associated with L-Cn levels as well as complete response in CHB patients following Peg-IFN antiviral therapy

In addition, signaling pathways such as NF-B, MAPKs, and Keap1-Nrf2-ARE etc., which affects physiological functions of ROS, are also discussed in details