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[572] used shRNA to reverse the HIF-2-induced activation of the Hippo signaling pathway and glutaminolysis, thereby reducing HSC activation markers

DNA repair and damage response BRCA2 BRCA2 has not typically been associated with low mutational burden in GBM, with expression of BRCA1 and BRCA2 mutant GBM found in 1.4% of patient cases [49]

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Coxsackievirus has been implicated in autoimmune thyroiditis and possibly GD, while human herpesvirus-6 (HHV-6) has also been reported in some autoimmune disorders

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