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sinensis was reported to enhance the immunity in mice exposed to ionizing radiation by reducing oxidative injury and modulating the secretion of cytokines (IL-4, -5 and -17) (Zhang et al., 2011)

At an oral dose of 560 mg of silymarin and comparing with non-cirrhotic HCV subjects, NAFLD subjects had blood AUC 048 values for silybin A and silybin B which were 1.5-fold and 2.1-fold greater, respectively, than found in healthy controls

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Furthermore, mapping studies using pulldown and competition assays demonstrated that HAP1 interacts with sortilin and proBDNF [72]