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Bayr, H

J Manag Care Spec Pharm

It has been proposed that the western diet-induced intestinal ecological dysregulation and the altered intestinal barrier function can induce neuroinflammation, in turn can activate Toll-like receptors, then cause a proinflammatory response and the intestinal glial activation, ultimately contributes to the -synuclein pathology in the pathogenesis of PD (129)

Neurochem Int 50:418426 Dringen R, Pfeiffer B, Hamprecht B (1999) Synthesis of the antioxidant glutathione in neurons: supply by astrocytes of CysGly as precursor for neuronal glutathione

It is associated with significant burden at the patient and societal level

These include: Reference ranges for measuring GSH in the body are lacking and muddied by individual variation