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Moreover, multiple in vitro (Reference Hseu, Lo and Korivi64,Reference Ko, Kim and Ahn65) and in vivo (Reference Salama and Omar66,Reference Dare, Channa and Nadar67) studies suggest that ergothioneine activates the transcription factor nuclear factor erythroid 2-related factor 2 (Nrf2), which triggers the cellular antioxidant defence system

Sarkar S, Deyoung T, Ressler H, Chandler W

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Mitochondria often referred to as the powerhouses of the cell, play a crucial role in maintaining cellular function by providing energy and regulating various physiological and pathological processes