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ROS enhances inflammation by activating MAPK, which subsequently phosphorylates downstream proteins to upregulate the expression of pro-inflammatory genes such as IL-6, TNF-, and IL-1 [90]

The effectiveness of Nascobal Nasal Spray in patients with nasal congestion, allergic rhinitis and upper respiratory infections has not been determined

Our observations suggest that pre-emptive genotyping of CYP2C9 and GSTM1 may aid in selection of more effective prophylaxis to reduce HC development in pediatric patients undergoing allogeneic HSCT