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A patient on semaglutide or tirzepatide at an appropriate therapeutic dose, typically nine to twelve or more months into therapy, with a documented plateau over at least four to six weeks

Additionally, vegans or vegetarians, who may not obtain sucient B12 from their diet, and individuals with specic neurological symptoms or conditions might also consider this form of supplementation.

Even with B12 in the diet, absorption depends on stomach acid and a protein called intrinsic factor, both of which decline with age and with certain medications

In fact, most people are able to get enough vitamin B12 through diet alone