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Thus, the protective properties of ascorbate (1 g/day) are based on the elimination of the action of various proteasome inhibitors [104,105] and the promotion of the removal of oxidatively damaged proteins from the cytoplasm of cells (Figure 2)

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There is evidence for replacement of Ib inhibition with facilitation in hemiplegic individuals with supraspinal lesions, leading to simultaneous cofiring of agonist and antagonist muscle groups (20)

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