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3.6 Melanogenesis reduction Ultraviolet radiation stimulates melanogenesis through activation of the microphthalmia-associated transcription factor (MITF)-regulated pathway, promoting tyrosinase (TYR)-dependent melanin synthesis in melanosomes to protect against DNA damage, while excessive production leads to hyperpigmentation disorders (Kim et al., 2021)

doi: 10.1007/s12325-020-01464-1 61 JohansenPHuntBIyerNNDang-TanTPollockRF

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Farthing et al

As a result, ammonium ions are trapped in the intestinal lumen, and there is a nett flux of ammonia form the bloodstream into the intestinal lumen.

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