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For a subcutaneous injection, which goes into the fatty tissue just beneath the skin, a 45-degree angle is best

(PubMed) Carr AC, Pullar JM, Bozonet SM, Vissers MC

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Compounds spanning 100-fold IC50 values for NNMT inhibition were selected on the basis of positional substitutions around the N-methylated quinolinium scaffold to obtain an estimate of drug-like oral absorption/bioavailability properties and guide the choice of inhibitors for in vitro and in vivo phenotypic studies