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8.3.2 Brain-derived neurotrophic factor-loaded NPs BDNF is a critical protein belonging to the neurotrophin family, playing a significant role in neuronal growth, synaptic plasticity, and overall brain health (180)

Research specifically on the combined three-peptide formulation is limited

Clitoria ternatea root extract treatment during growth spurt period enhances learning and memory in rats

In the cellular context, the protein HELLS, a member of the SNF2 ATPase family, is important for new DNA methylation through its interaction with DNMT3b (86)

Classical methods of rational sequence and structure-based peptide designs have now expanded to include the screening of large peptide libraries to identify functional hits

Cell lines and patient-2D cultures: cybrids, primary fibroblast/lymphocytes, neuronal progenitors, or differentiated neurons from patient-iPSC