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For instance, Plagiochin E, a macrocyclic bis(bibenzyl) compound isolated from Marchantia polymorpha , exhibits antifungal activity by targeting chitin synthesis

Second, the GLDH enzyme uses oxidized cytochrome c as the only electron acceptor (Millar et al., 2003)

APAP hepatotoxicity occurs through formation of the noxious NAPQI metabolite, which is present in excessive quantities, as augmented by features of glutathione (GSH) depletion, oxidative stress and mitochondrial dysfunction leading to depletion in adenosine triphosphate (ATP) stores

Saville et al., 2019

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