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Long-term safety including hormone interaction, cancer risk, and effects on reproductive health has not been studied

Antidepressants Many antidepressants (medications used to treat depression and anxiety disorders) can cause or worsen tinnitus

739 In the MCAO/R model of rats, the expression of SLC7A11 is downregulated, accompanied by inhibition of GSH and GPX4, suggesting that the deficiency of xCT in cerebral I/R injury may be the main cause of lipid peroxidation and ferroptosis

doi: 10.6004/jnccn.2016.0051 153 NaxerovaKReiterJGBrachtelELennerzJKVan De WeteringMRowanAet al

Natural compounds attenuate combined chromium and arsenic-induced oxidative stress and nephritic apoptosis by activating the Nrf2/Keap1 signaling and associated xenobiotic metabolizing enzymes