d na glutathione D-na Vietnam OS induced by glutathione depletion

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Based on individual gene expression results, aged sample replicates CMO303 (WT) and CMO306 ( Mda5 -/- ) were found to be unfit for further analysis and were excluded

The individual baseline GH levels attributed to endogenous GH production ranged from below the limit of quantification up to 6.8 ng/mL (Table 1)

it is a biological shortage

Instead, therapeutic modulation of GSH must be tailored to disease context, reflecting the fundamental GSH paradox: whereas cancer therapy often seeks to deplete elevated GSH to induce oxidative stress and cell death, neurodegenerative and inflammatory diseases may require restoration of GSH homeostasis