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Consequently, non-enzymatic crotonylation is regarded as a protein modification mechanism that directly and rapidly responds to changes in cellular metabolic state, working in concert with the canonical enzymatic modification pathway to constitute a dynamic and complex regulatory network for crotonylation [126]

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Owing to significant differences in metabolite concentrations, the detection of low-concentration metabolites demands increased sensitivity from these technologies

Results over the nine trials were underwhelming, with most finding no impact from the antioxidants on peoples risk of developing cancer or the likelihood that they would survive it

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People with MCAS may also have other mast cell disorders such as mastocytosis or hereditary alpha tryptasemia syndrome (HATS)