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Do either of these have long-term outcome data

Dawson, S

Regarding DM-associated gastrointestinal pathophysiology, studies demonstrate hyperglycemia-driven systemic inflammation through three key mechanisms: (1) Downregulation of intestinal tight junction proteins (e.g., ZO-1) enhances gut permeability, enabling systemic translocation of pathogen-associated molecular patterns (PAMPs, e.g., LPS)

doi: 10.1158/0008-5472.CAN-10-2668 108 La MonicaSMinariRCretellaDFlamminiLFumarolaCBonelliMet al

Live cells emitted green fluorescence while dead cells showed red fluorescence

In this review, we detail finding related to mTORopathies that relate to dysfunctional brain metabolism including abnormal changes in macromolecule processing and mitochondrial metabolism