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(67) found that quercetin can reduce the inflammatory factor IL-1 in a rat model of cerebral ischemia caused by IL-1 and IL-6 to alleviate the severity of cerebral ischemia

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The downregulation of JAK/STAT and NF-B signaling by H 2 S also helps recover the protective effects of preconditioning against ischemia-reperfusion injury in aging hearts by reducing ROS levels (Li et al., 2016)