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Dietary and metabolic effects on intestinal stem cells in health and disease

In addition, it remains very uncertain whether gut microbiome is a causative factor or a consequence of the disease, which necessitates more thoughtful approaches, including colonization of germ-free mice with gut microbiome associated with the disease which might offer more insight into the role of these bacteria in the disease pathogenesis

The mutations of IDH1 or IDH2 exhibit a neomorphic activity by converting glutaminederived KG to 2hydroxyglutarate (2HG), which competitively inhibits KGdependent histone and DNA demethylases (Dang et al , 2010

HGF is a potent neurotrophic factor that promotes neurogenesis and has been shown to have neuroprotective effects in neurodegenerative diseases (reviewed in: 37 )

International Journal Of Molecular Sciences 2024, 25: 4484

Effect of in ovo feeding of amino acids and dextrose solutions on hatchability, body weight, intestinal development and liver glycogen reserves in newborn chicks