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Description

Both cytokines, are key mediators in the production of IgE, recruitment of inflammatory cell into the airways, hyperplasia of goblet cells and modulates airway hyperresponsiveness (Santini et al., 2017)

1998;26(11):113443 ( Article )

Cheng notes

This family of enzymes is central to the respiratory burst in immune responses and the generation of H 2 O 2 as a second messenger in cellular signalling, development, and environmental sensing across kingdoms 1,2

To shed more light on the identity of the substrate of arGSTs, we performed labelling experiments with H 2 18 O, exploiting the same principle of 18 O incorporation as described earlier