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Human and Ecological Risk Assessment

Wicherts et al

K.ZhuX.GaierE.BushA

The instability of JKE-1777 may explain its diminished potency compared to other ML210-derived compounds, as the degradation products of JKE-1777 are inactive (Figures S6C and S6D)

Additionally, -Glutamyl transferase (GGT), another enzyme that is involved in the biosynthesis of -glutamyl tripeptide, catalyzes the transfer of -glutamyl group of glutathione to amino acids or peptides