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[7] A conserved ncRNA upstream of the icd gene which codes for NADP + -dependent isocitrate dehydrogenase (IDH) has been reported in bacterial genomes, due to its characteristics this ncRNA resembles previous regulatory motifs called riboswitches, icd-II ncRNA motif has been proposed as a strong candidate riboswitch

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Chronic inflammation, seen in conditions like rheumatoid arthritis and inflammatory bowel disease, is both a cause and consequence of sustained oxidative stress [13]

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Studies comparing routes consistently show IV glutathione produces five to ten times higher peak plasma concentrations than oral dosing (PubMed PMID: 24791752)

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