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Sep 17 2021;22(18)doi:10.3390/ijms221810043

N-linked glycans in the variable domain of IgG anti-citrullinated protein antibodies predict the development of rheumatoid arthritis

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On the other hand, monoclonal antibodies directed to the catalytic domain of CA IX, including G250, VII/20, and MSC8, recognize conformational epitopes that are disrupted in reducing and denaturing conditions [91,92,93]