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Toxicol Pathol 36(7):932943 Pang CC-C, Kiecker C, OBrien JT et al (2019) Ammons Horn 2 (CA2) of the hippocampus: a long-known region with a new potential role in neurodegeneration [J]

Similarly, most other critical metabolites can be obtained by other amino acids that are provided with no limitations to the tumor 240,241,242,243,244,245

One side benefit of SAM-e is that it also is used as a natural anti-depressant because it is involved in the creation of the chemicals dopamine and serotonin (National Center for Complementary and Integrative Health [NCCIH], 2022)