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For transcriptome analysis, Piper nigrum accession 4226 a drought-tolerant genotype identified through field screening ( For physiological and biochemical analysis, leaves were collected from six-year-old, field grown 4226 plants that experienced one month of natural drought stress (1112% soil moisture) during the flowering stage, along with fully irrigated control plants maintained at 1920% soil moisture

In AD patients, NF-Bis positively correlated with the expression level of miR-146a-5p, but there is a negative correlation between NF-B mRNA and TIGAR mRNA, and between miR-146a-5p and TIGAR mRNA (Lei et al., 2021)