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Our findings revealed that the Morgan-fingerprint-based XGB model achieved the highest discrimination, demonstrated by an area under the receiver operating curve (AUROC) of 0.828 and area under the precisionrecall curve (AUPRC) of 0.237, consistently outperforming descriptor-based models

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(Paw & Shulman 2025) dosing (& when to stop) IV acetylcysteine for acetaminophen toxicity: Standard dosing The 24-hour IV regimen is generally used: Extremely safe

While the mechanisms underlying APAP-mediated lysosomal instability or permeabilization are not fully understood, the iron chelator desferal prevented mitochondrial depolarization and hepatocellular death after APAP exposure (Kon et al., 2010)

Eur J Appl Physiol 121 , 32833295 (2021)

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