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In ASD and Fragile X Syndrome (FXS), in which patients do not have seizures, CBD treatment has been proven to help in both animal and human models

doi: 10.1038/s41565-023-01346-x

140 Conversely, poor sleep can change the composition of the gut microbiome, which may contribute to metabolic disturbance and immune, neurologic, and hormonal dysregulation

The 12-week placebo-controlled trial did not reach its primary endpoints, but the 36-week open-label extension trial showed significant improvements in 6-minute walk distance (+95.9 m, p=0.024), symptom scores, and knee extensor muscle strength