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1 Introduction Discovered 30 years ago, the dopamine D 4 receptor (D 4 R) initially drew attention due to its strong affinity for the atypical antipsychotic clozapine, an affinity found to be significantly higher than for the previously discovered D 1 , D 2 and D 3 receptors (D 1 R, D 2 R and D 3 R) ( 4 R antagonists

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Potency Metrics: EC50: 1.3 0.4 nmol/L for GH release in vitro (rat pituitary cells)

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This significantly enhances the bioavailability of glutathione, ensuring it reaches the target cells and tissues in higher concentrations compared to traditional oral supplements