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Common side effects include rounding of the face (moon face), acne, increased body hair, diabetes, weight gain, high blood pressure, cataracts, glaucoma, increased susceptibility to infections, muscle weakness, depression, insomnia, mood swings, personality changes, irritability, and thinning of the bones (osteoporosis) with an accompanying increased risk of compression fractures of the spine

Cytotoxic amyloid oligomers triggered the release of drugs and fluorescent dyes by disrupting the lipid membrane

doi: 10.1002/jor.23728, 38

(ii) the establishment of standardized analytical techniques and production protocols

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Excess glutamate leads to over-stimulation of postsynaptic glutamatergic receptors, particularly NMDARs and AMPARs, allowing calcium to enter the cell, causing neuronal depolarisation and further neuronal death (Glotfelty et al., 2019), Inhibition of glutamate release, enhancement of glutamate clearance and blockade of glutamate receptors may be major directions for future stroke research