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Ethics statement The studies involving human participants were reviewed and approved by Ethical and Experimental Committee of Ningxia Medical University

coli synthesizes TML to a much lesser extent than eukaryotic cells (Klagsbrun and Furano, 1975

Administration of low-dose subcutaneous Ig (0.06 g/kg/month for 5 weeks) in an uncontrolled case series ( n = 17 with infection-related ME/CFS) yielded positive outcomes

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Therapies that indirectly affect the innate CNS immune response, including staphylococcal vaccine (Zachrisson et al., 2002, 2004), Bacillus CalmetteGurin (BCG) vaccine (Snchez-Ramn et al., 2018), rintatolimod (Strayer et al., 2020) and stellate ganglion block should also be considered (Lipov et al., 2020

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