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mBio 4 , e00810-13 (2013)

Nuttle, X

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Studies confirm that in nasopharyngeal carcinoma models, the enzyme ACSL4 promotes ferroptosis by driving lipid peroxidation, which directly leads to the repolarization of tumor-associated macrophages ( TAM ) from a pro-tumor M2 phenotype to an anti-tumor M1 phenotype (146)