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In general, CSE is more highly expressed than CBS in peripheral organs, including the liver and kidney, with a ratio of about 60:1 in the liver and about 20:1 in the kidney [129]

Vigna and Naldini, 2000, J

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Mouse Model For Studying The Efficiency Ofgenetic Vaccines In Transfecting Human Muscle Cells And Inducing Human Immune Responses In Vivo There is a lack of suitable in vivo models for studies of the efficiency of genetic vaccines and the vast majority of studies are performed on the mouse model, in which it is sometimes difficult to predict whether the results obtained reliably predict similar vaccinations in humans because of the complexity of events occurring after genetic vaccination A lack of suitable in vivo models has hampered studies of the efficiency of genetic vaccines in inducing antigen expression in human muscle cells and in inducing specific human immune responses