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The differential equation for cytosolic GSH is: The first term is the synthesis of GSH from glycine and glutamyl-cysteine

doi: 10.1038/onc.2016.499 141 MartinoJJWallBAMastrantoniEWilimczykBJLa CavaSNDegenhardtKet al

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Selective serotonin reuptake inhibitors (SSRIs), commonly prescribed for depression, can increase the risk of bleeding when combined with ibuprofen

Consistent with the toxicity of isoniazid in slow acetylators, there is an increased incidence of other drug toxicities in subjects carrying defective alleles, such as lupus erythematosus in patients treated with hydralazine or procainamide (Sim et al., 1988), and haemolytic anemia and inflammatory bowel disease after treatment with sulfasalazine (Chen et al., 2007)

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