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This integrated biochemical profiling allowed for the evaluation of both enzymatic inhibition and oxidative stress induction, providing a comprehensive understanding of how the methanolic and nanoemulsion formulations of Araucaria heterophylla and Azadirachta indica disrupt the detoxification and antioxidant defense mechanisms of Cx

Castrillo-Viguera C, et al

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Titilayo GI, Adeyemi E

Reactive oxygen species (ROS), pivotal to disease progression, are generated via multiple pathways, including TLR4-mediated NADPH oxidase (NOX) activation following macrophage infiltration [15]