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The dotted line represents P =0.05

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In Vitro CellDevBiol-Animal

SOD1 (superoxide dismutase) GHK-Cu enhances endogenous antioxidant defenses by increasing SOD1 expression, which neutralizes superoxide radicals implicated in photoaging and oxidative DNA damage

The pattern is that both are GI-forward drugs, but retatrutides glucagon activity adds a cardiovascular consideration (heart rate) that cagrilintides amylin mechanism does not, and the same potency that produces retatrutides larger weight loss is associated, in indirect analyses, with a heavier adverse-event load