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Traditional radiation treatment and chemotherapy are almost completely ineffective for RCC, and the development of targeted drugs against VEGFR and its ligand VEGF is considered to be the primary therapeutic intervention required for patients with advanced RCC (132)

Curi TC, De Melo MP, De Azevedo RB, Zorn TM, Curi R

Oxidative stress therefore leads to the accumulation of ROS, which, in turn, causes damage to our cells

Its also sourced from extrapolated animal research

Although this review provides important information for Parkinsons disease and the possibility of providing natural materials to reduce the damage that occurs in nerve cells, the following points are still needed: (1) the chemical components of each plant or animal extract, (2) the mechanism of action of each extract, in terms of molecular and biological pathways associated with it, (3) information on the effectiveness and safety of each compound of the extracts applied against Parkinsons disease, (4) details on therapeutic results for each compound in patients by conducting many clinical studies and not being satisfied with the results obtained from animal models ( in vivo ) or cell lines ( in vitro ) for Parkinsons disease

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