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Authors contributions MFM and SET contributed to the conception of the study, designed the meta-analysis, and extracted the data

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The 3.0 g/d group produced considerably less MP on all five sprints (-1.5%, - 7.6%, -9.0%, -7.0, -3.3) and the 4.5 g/d group had lower values of MP on sprints two through five (-2.5%, -3.6%, -6.9%, -1.1)

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Although CRP levels were significantly increased in the placebo, but not in the LCLT group, due to the low infectivity rate in the Cohort 1 we cannot correlate with disease progression

The main hypotheses involved in the pathogenesis of PD were as follows: oxidative stress (Trist et al., 2019), mitochondrial dysfunction (Navarro and Boveris, 2009), excitotoxicity (Ambrosi et al., 2020), and the theory of gut origin (Postuma, 2015)