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For the GSH/GSSG redox state, severe asthmatics in the Fitzpatrick study (23) have a mean E h GSH/GSSH of 90 mV similar to asthmatics admitted to the PICU in this study (E h GSH/GSSG 93 mV)

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In a mouse model of FA-induced AKI, Fer-1 significantly restored renal function, but apoptosis inhibitors were not effective, suggesting a dominant role for ferroptosis in FA-induced AKI [136, 163]

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