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Thus, it can be hypothesized that temporal changes in net proteolytic activity in human milk contribute to the FAA dynamics, although this is unlikely as levels of all major human milk proteases and anti-proteases decrease during lactation, along with levels of their substrates (50, 58)

doi: 10.1016/j.phytochem.2007.03.038 61 RozemaJ.Van De StaaijJ.BjrnL

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Am J Hematol 2008;83:4824

And often its overexpression was closely related to the poor prognosis of patients [30]

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