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Cell Cycle 18(2):22637 Almostafa MM, Mohamed ME, Younis NS (2024) Ameliorative effects of vanillin against pentylenetetrazole-induced epilepsy and associated memory loss in mice: the role of Nrf2/HO-1/NQO1 and HMGB1/RAGE/TLR4/NFB pathways

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Glucose taken up from the bloodstream through GLUT1 and GLUT4 transporters, is primarily metabolized by glycolysis

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They slow the disease rather than restoring lost function, and the evidence is specific to people who already have early Alzheimers with confirmed amyloid, though secondary prevention trials are now testing whether clearing amyloid in cognitively normal but amyloid-positive people can delay the disease

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Therefore, it is crucial to ensure the genetic integrity of iPSCs to maximize their potential in regenerative medicine [59]

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