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Some derivatives are also capable of blocking the JAK/STAT3 pathway or inhibiting NLRP3 inflammasome activation (Witaicenis et al., 2018)

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Golimumab Golimumab is a monoclonal antibody of the IgG1- class that targets TNF-

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doi: 10.1124/jpet.102.045351 313 SafronovaVGVulfiusCAShelukhinaIVMaltsevaVNBerezhnovAVFedotovaEIet al

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