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7 Treatment strategies for breast cancer The strategies for treating breast cancer have progressed in tandem with our understanding of the diseases molecular and pathological heterogeneity, surpassing the notion of a universal approach

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To assess the activation of the TGFB/SMAD pathway, the expression and localization of phosphorylated SMAD2 and SMAD3 (pSMAD2/3) were examined in both cultured cells and xenograft lesions (Fig