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After treatment initiation and dose increases, patients should be observed carefully for signs and symptoms of pancreatitis (including persistent severe abdominal pain, sometimes radiating to the back and which may or may not be accompanied by vomiting)

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Subcutaneous (Injectable): 1.25 mg to 2.5 mg daily

Patients on Specific Medications: Certain medications, like proton pump inhibitors or metformin, can interfere with B12 absorption, making monitoring and supplementation necessary

Days 3 to 7: Clearer Head, Steadier Mood By the end of the first week, the early surge tends to settle into a more even supply

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