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This highlights the necessity of proactive screening and early intervention to prevent the progression of these complications [39]

doi: 10.1002/(sici)1096-8628(19980428)77:1 3.0.co;2-o

Historical data helps identify trends and optimize treatment protocols over time

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In this review, we will focus on the metabolic effects of IGF-1, the concept of metabolic syndrome and its clinical manifestations (impaired lipid profile, insulin resistance, increased glucose levels, obesity, and cardiovascular disease), discussing whether IGF-1 replacement therapy could be a beneficial strategy for these patients