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For example, -KG acts as a cofactor for the activation of the histone demethylase JMJ family (Jumonji) to promote histone demethylation (102, 125)

This is further demonstrated by immunostaining of Day 45 iHLOs, which shows a significant increase and clustering of DES-expressing cells forming a solid structure distinct from the cystic structure composed of KRT7- or CYP3A4-expressing epithelial cells (Supplementary Fig

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doi: 10.1096/fj.202101722R 85 MarinoJMaubertMEMeleARSpectorCWigdahlBNonnemacherMR

IUBMB Life 68(3):220231 Chen J, Li X, Ge C, Min J, Wang F (2022a) The multifaceted role of ferroptosis in liver disease

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