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This dual Cas9 system takes advantage of different protospacer adjacent motif (PAM) sequences recognized by Streptococcus pyogenes Cas9 (SpCas9) versus Staphylococcus aureus Cas9 (SaCas9), enabling simultaneously knocking out two genes (Fig

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2.9 RNA sequencing For RNA sequencing, HEK293T cell lines were seeded in 6-cm dishes and treated with 2.5 M of FAC and 5 M of 8-HQ

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Prevention of irradiation-induced esophagitis by plasmid/liposome delivery of the human manganese superoxide dismutase (MnSOD) transgene

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Nat Rev Drug Discovery (2019) 18:17596

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