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Pathophysiology of cALD Pathologic hallmark of cALD is inflammatory cerebral demyelination (Figure 1)

As you can see, the deeper scars are still around, but gradually fading

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10.1111/j.1365-2958.2012.08081.x 4 BashiriG.BakerE

It has been demonstrated that small molecules such as the PI3 kinase inhibitor LY294002 effectively inhibited insulin signaling 8 , whilst Sekine and colleagues (2012) 7 demonstrated that the simple omission of insulin efficiently generated DE

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