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KRAS-mutant lung cancer cells enhance the biosynthesis of saturated and monounsaturated fatty acids, as well as their corresponding phosphatidylcholine, by upregulating FASN, thereby conferring resistance to oxidative damage and ferroptosis

View Study Lospinoso K, Strowd L, Feldman S

Decreased proliferation and erythroid differentiation of K562 cells by siRNA induced depression of OCTN1 (SLC22A4) transporter gene

Therefore, FSP1 inhibitors can be combined with GPX4-targeting agents such as DHA for the treatment of GBM

"Coronavirus (COVID-19) Update: FDA Authorizes Updated (Bivalent) COVID-19 Vaccines for Children Down to 6 Months of Age"

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